NFL odds, picks for Week 12: Proven computer model loving Seahawks, Colts –

The remaining Week 12 NFL schedule features a dozen games, and if you believe the latest NFL odds and spreads, several will be nail-biters. In Houston, the Texans host the division-rival Titans on Monday Night Football. We now know that Titans quarterback Marcus Mariota will start on Monday after suffering a neck injury. Money has been pouring in on the Titans as a result, dragging the line down from Houston -5.5 to -4. In what could be one of the highest-scoring NFL games of the week, the Buccaneers host the 49ers. The Bucs are favored by two in that matchup after the line opened at a field goal, one of the tightest NFL spreads of the week. The Over-Under for 49ers vs. Buccaneers stands at 54, down slightly from an open of 55.5, but still the highest on the remaining Week 12 NFL schedule. With NFL odds large and small to choose from, check out the latest Week 12 NFL picks and predictions from SportsLine’s advanced computer model before locking in any plays of your own.

SportsLine’s proprietary computer model went 176-80 last season and beat over 95 percent of CBS Sports Office Pool players in 2016 and ’17. It also performed better than 98 percent of experts tracked by during that span. Additionally, it went 48-34 on A-rated picks against the spread last season, and $100 bettors who have followed it the past two seasons are up nearly $4,000. 

The model has continued to nail its top-rated picks in 2018, entering Week 12 on a blistering 12-0 run. For the season, it is now 26-9 on all top-rated picks, extending its two-year run to a strong 74-43. And when it comes to all straight-up picks, the model is 105-53 this season, again ranking in the top 10

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